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  • Experts from Brigham Young University in Utah discovered that addiction comes from an 'overcorrection' inside the brain, a PsychCentral report said.

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  • Evidence is increasing that every addiction without exception is related to issues with the brain's reward center, specially the mesolimbic system. This section of the problem regulates reward responses in acquiring food and sex, as well as in nurturing infants and children. One of the most important neurotransmitters linked to reward responses, both after they malfunction and whenever they function properly, is dopamine. What makes opiates unique is that it, among other neurotransmitters modulates "the volume of dopamine released in in reply to a stimulus"(Bostwick & Bucci, 2008).

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    Researchers discovered that participants investing in this drug to get a year, lost weight within a month and have kept the weight off during the entire 56 weeks of the study. Contrave is a combination of the drugs naltrexone and bupropion, which usually reflect a whole new trend of weight-loss drugs which are made up of multiple active ingredient, that might make them more potent and safer.

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    Other people who should avoid using Contrave are patients being affected by bulimia, anorexia nervosa, anyone using opiods, and patients undergoing an 'abrupt discontinuation of alcohol, benzodiazepines, barbiturates and antiepileptic drugs.' Lastly Concave shouldn't be prescribed for girls who are pregnant or wanting to become pregnant.

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    Researchers found that participants using this drug for the year, dropped a few pounds within 4 weeks and have kept the extra weight off throughout the 56 weeks of the study. Contrave is really a combination with the drugs naltrexone and bupropion, which usually reflect a brand new trend of weight-loss drugs that are made up of several active ingredient, which may make them more effective and safer.

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    Seizures certainly are a side effect with Contrave and shouldn't be taken in those with seizure disorders. The drug may also raise blood pressure level and heartbeat, and mustn't be used in those with a history of heart attack or stroke in the earlier six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy with all the drug.

    The FDA also warned that Contrave can raise blood pressure and heartbeat and must 't be used in patients with uncontrolled high hypertension, and also by you aren't heart-related and cerebrovascular (circulation system dysfunction impacting mental performance) disease. Patients with a history of heart attack or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes using a boxed warning to alert health care professionals and patients to the increased risk of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for smoking cessation.

    To take care of the most current articles from Wendi, the Indiana Addiction Recovery Examiner, go through the subscribe link on top of the page to obtain email notification when new content is published. Please leave a comment for just about any article.

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  • It was discovered that naltrexone and bupropion combined, that could be marketed later on as Contrave, provide better weight loss results than eating and working out alone.

    Using two separate drugs to shed pounds can be very effective there are combinations in front of the FDA now awaiting approval. When dealing with fat loss and the people who go through it one should err to the side of caution and let the FDA do its job and demand some investigation be done so that the public is aware of the side effects and risks of the medications before we bring them. Keep in mind that drug companies have been in business to make money and that they would say almost anything to keep people on their medications.

    Researchers found out that participants using this drug for any year, lost excess weight within one month and have kept the load off throughout the 56 weeks from the study. Contrave is really a combination in the drugs naltrexone and bupropion, which generally seems to reflect a brand new trend of weight-loss drugs which can be made up of many active ingredient, which may make them more potent and safer.

    Combo-pilling could be the newest fad or in addition to this the newest to come under scrutiny and thus it is just more publicly known recently, comb-pilling to lose weight has been around since the eighties. The biggest reason that by using a combination of pills is starting to become popular could be the fact that at the time of right now there are no long term prescription weight loss supplements that have been authorized by the FDA aside from orlistat. The truly disturbing part is doctors are prescribing these combinations of medications and some of the combinations have been rejected or have yet to be authorized by the FDA.

    Seizures are a side effect with Contrave and shouldn't be taken in people with seizure disorders. The drug also can raise blood pressure and heartrate, and mustn't be used in people who have a history of cardiac arrest or stroke in the previous six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy while using drug.

    The FDA also warned that Contrave can raise blood pressure and heartbeat and must not be used in patients with uncontrolled high blood pressure level, as well as by you aren't heart-related and cerebrovascular (circulation dysfunction impacting your brain) disease. Patients using a history of heart attack or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes having a boxed warning to alert physicians and patients to the increased likelihood of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for quitting smoking.

    Suboxone includes two drugs; buprenorphine and naloxone. The naloxone is irrelevant when the addict uses the medication properly, but if your tablet is dissolved in water and injected the naloxone will cause instant withdrawal. When suboxone can be used correctly, the naloxone is destroyed inside liver shortly after uptake in the intestines and contains no therapeutic effect. Buprenorphine will be the active substance; it can be absorbed beneath the tongue (and during the entire mouth) but destroyed from the liver if swallowed. There is a formulation of buprenorphine without naloxone called subutex; I have used this formulation in the event the patient has apparent problems from naloxone, including headaches after dosing with suboxone. I have treated addicts who have had gastric bypass, the place that the first the main intestine is bypassed and also the stomach contents empty in to a more distal section of the small intestine. In such cases the naloxone escapes ?first pass metabolism', the task with normal anatomy where the drug is taken up from the duodenum and transferred straight away to the liver with the portal vein, where it can be quickly and completely destroyed. After gastric bypass naloxone can be taken on by servings of the intestine that are not served by the portal system, causing blood degrees of naloxone sufficient to cause brief, relatively mild withdrawal symptoms.

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